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SU2C Scientific Research Teams

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Jeffrey A. Drebin, MD, PhD

Scientific Research Team:
Jeffrey A. Drebin, MD, PhD

Jeffrey A. Drebin, MD, PhD

The SU2C–National Science Foundation- Lustgarten Foundation-V Foundation Pancreatic Cancer Convergence

Dr. Jeffrey A. Drebin is the Chairman of the Department of Surgery at Memorial Sloan Kettering Cancer Center (MSK). He received his M.D. and Ph.D. degrees from Harvard, where his Ph.D. work involved the development of the first monoclonal antibodies targeting the HER2/neu oncogene.  He subsequently performed his surgical training in General Surgery and a Fellowship in Surgical Oncology at the Johns Hopkins Hospital.  Upon completing his clinical training, Dr. Drebin was recruited to Washington University School of Medicine in 1995 as Assistant Professor of Surgery by Dr. Samuel Wells.  He was promoted to Associate Professor of Surgery, with tenure, in 1999, and then Professor of Surgery and of Molecular Biology & Pharmacology in 2002.  Dr. Drebin’s laboratory has studied HER2/neu signal transduction in breast and pancreas cancer, and continues to examine beta-catenin signaling in colon cancer.  He has received research support from the NIH, the Department of Defense, and the Burroughs Wellcome fund for this work.  Multiple surgery residents who worked in Dr. Drebin’s laboratory have themselves gone on to successful academic surgical careers. 

In 2004 Dr. Drebin was recruited to the Department of Surgery at the University of Pennsylvania School of Medicine as Chief of the Division of Gastrointestinal Surgery and Vice-Chair for Research, receiving the William M. Measey Professorship in Surgical Research.  In 2009 he was appointed Chair of the Department of Surgery at the University of Pennsylvania and the John Rhea Barton Professor – the oldest endowed professorship in an American medical school.  Dr. Drebin is involved with multiple organizations focusing on clinical surgery and cancer research, currently serving as President of the Society of Surgical Oncology, Past-President of the Philadelphia Academy of Surgery and Past-President of the Society of Clinical Surgery.  He has previously served as a member of the Board of Scientific Advisors of the U.S. National Cancer Institute, on the Executive Committee of the American College of Surgeons Oncology Group and as Chair of the Pancreas Cancer Disease Site Sub-Committee of the Commission on Cancer of the American College of Surgeons.  Dr. Drebin also served as co-Principal Investigator on a 22 million dollar Stand Up to Cancer grant supporting the first Pancreas Cancer Dream Team.  In 2013 he was elected to the National Academy of Medicine (formerly the Institute of Medicine of the National Academy of Sciences (USA). He was previously the John Rhea Barton Professor and Chairman of the Department of Surgery at the Perlman School of Medicine of the University of Pennsylvania (UPenn).